Commenting on the fact that the oldest fragments of the Greek Septuagint do contain the divine name in its Hebrew form, Dr. P. Kahle says: “We now know that the Greek Bible text [the Septuagint] as far as it was written by Jews for Jews did not translate the Divine name by kyrios, but the Tetragrammaton written with Hebrew or Greek letters was retained in such MSS [manuscripts]. It was the Christians who replaced the Tetragrammaton by kyrios, when the divine name written in Hebrew letters was not understood any more.” (The Cairo Geniza, Oxford, 1959, p. 222)

Around 245 C.E., the noted scholar Origen produced his Hexapla, a six-column reproduction of the inspired Hebrew Scriptures: (1) in their original Hebrew and Aramaic, accompanied by (2) a transliteration into Greek, and by the Greek versions of (3) Aquila, (4) Symmachus, (5) the Septuagint, and (6) Theodotion. On the evidence of the fragmentary copies now known, Professor W. G. Waddell says: “In Origen’s Hexapla . . . the Greek versions of Aquila, Symmachus, and LXX [Septuagint] all represented JHWH by ΠΙΠΙ;

The so-called Christians, then, who “replaced the Tetragrammaton by kyrios” in the Septuagint copies, were not the early disciples of Jesus. They were persons of later centuries, when the foretold apostasy was well developed and had corrupted the purity of Christian teachings.​—2Th 2:3; 1Ti 4:1.